Uncovering the Genetic Architecture of Parkinson’s Disease

The Global Parkinson’s Genetics Program (GP2) is an ambitious program to genotype over 250,000 volunteers around the world to further understand the genetic architecture of Parkinson’s disease (PD). GP2 is a resource program of Aligning Science Across Parkinson's (ASAP) managed by the Coalition for Aligning Science and implemented by the Michael J. Fox Foundation.

Our Goal

To Genotype Over 250,000 Volunteers From Around the World.

Using this knowledge, we’ll accelerate the development and deployment of therapeutic strategies for PD and build a community to address the emerging needs in PD research.

Here’s How We Do It

  • Collecting Samples and Data From Around the World

    Our goal is to expand and include groups traditionally underrepresented in genetics research.

  • Building Global Will and Capacity

    We offer a robust set of resources for PD researchers, including global training programs and opportunities.

  • Harmonizing and Analyzing Data

    Our data is available to researchers across the world through Terra and Verily® Workbench cloud computing platforms in collaboration with AMP® PD. 

Our Global Research Community

GP2 is made up of hundreds of member organizations around the world that are coming together to create a global research community dedicated to rapidly addressing emerging research needs in PD. Our work is aimed at using genetics to accelerate the path to the development and deployment of therapeutic strategies for PD. Our Working Groups bring together specialists across a range of disciplines to assist with the operations and implementation of our program.

Meet the Community

A Global View of PD

GP2 serves as a central hub to generate the genetic data from studies across the globe and harmonize corresponding clinical data. GP2-generated genetic data are shared in a central computational workspace that is available to qualified researchers, as well as returned directly to contributing researchers, enabling GP2 to serve as both a discovery engine and capacity builder. This equips a global research collective with the skill sets, tools, and infrastructure to rapidly and efficiently address emerging research needs and questions.

Explore map

More than
415
Cohorts
More than
124k
Samples Completed
More than
415k
Samples Expected
More than
120
Organization Members

Unlocking Training Opportunities

GP2 offers a wide variety of training opportunities for early career (and beyond) researchers. From in-person workshops to online courses, there are many free resources for investigators available in multiple languages.

Explore training opportunities
WGS Data Analysis
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Return of Genetic Results
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Latest GP2 News

Learn more about activities from the GP2’s network.

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Supporting International Collaboration through the GP2 Visiting Scientist Program

September 15, 2026

GP2’s Visiting Scientist Program gave a neuropsychologist from Colombia the opportunity to explore how social and cultural factors influence cognitive health and assessment across diverse populations.
Watch: The Lancet Neurology Highlights GP2’s Multi-Ancestry Parkinson’s Study

September 11, 2026

A new video from The Lancet Neurology highlights GP2’s largest multi-ancestry genetic study of Parkinson’s disease to date and the importance of ancestral diversity in research.
The Jewish Chronicle: Study points to genetic variant in over 25 % of Ashkenazi Jews with Parkinson’s

September 6, 2026

In a new study, GP2 looked at the genetic architecture of Parkinson’s disease across participants of 11 different ancestries, making it the largest-ever global assessment of the genetic spectrum of the condition.